Dose Distribution Homogeneity between 3DBrachytherapy and Intensity Modulated Radiation Therapy Techniques in Cervix Cancer Tumors: A Comparative Approach

Aim: The purpose of this study was to compare the dosimetric results of the techniques (3DBrachytherapy
and intensity-modulated radiotherapy IMRT) in patients with locally advanced cervical
carcinoma (LACC).
Methods: There were 15 patients with locally advanced cervical carcinoma (LACC), after the
completion of external beam radiotherapy (EBRT) for the whole pelvic irradiation 45 Gy/25 fractions,
followed by 3D-Brachytherapy 24 Gy per weekly fractions and 36 Gy of IMRT per 18 fractions.
Coverage of targets volume and doses received by normal tissue were compared in two techniques.
15 patients of LACC treated with 3D-Brachytherapy were selected for this study. IMRT plans were
also created for all the patients. 3D-Brachytherapy and IMRT plans were compared on the basis of
target volume coverage, dose to Organs at risk (OAR’s), homogeneity index (HI) and conformity index
(CI).
Results: The results showed that D90% of HRCTV in the 3D-Brachytherapy was covered more than
D90% of PTV in the IMRT of prescribed dose, the D2CC and the V60Gy values of Bladder and rectum
were significantly lower than in 3D-Brachytherapy. The HI and CI in 3D-Brachytherapy were found
better than IMRT.
Conclusion: 3D-Brachytherapy significantly reduced the irradiated volume of OAR’s and improved
dose coverage in tumor volume compared to that by IMRT.