Glycaemic Evaluation of Murraya koenigii in Alloxan-induced Diabetic Rabbits

Akande, T. and Balogun, S. T. and Abdullahi, H. and Ogundeko, T. O. and Ramyil, M. S. (2015) Glycaemic Evaluation of Murraya koenigii in Alloxan-induced Diabetic Rabbits. International Journal of Biochemistry Research & Review, 7 (4). pp. 175-181. ISSN 2231086X

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Abstract

Background: Study was aimed to evaluate the antidiabetic activity of Murraya koenigii, a traditional medicinal plant (Curry leaf) in normoglycemic and alloxan-induced diabetes rabbits.

Methods: Antidiabetic activity of aqueous extract of M. koenigii in 100, 200 300 mg/k doses was determined by estimating blood glucose before and at 1, 2, 4, 8, 24, and 72 hours post treatment intervals in treated rabbits.

Results: Aqueous extract of Murraya koenigii showed a dose dependent antidiabetic activity with maximum effect established at 300 mg/kg. The extract also exhibited a significant (p<0.05) dose- dependent hypoglycemic effect on normal and alloxan-induced diabetic rabbits.

Conclusion: Murraya koenigii causes a reduction in blood glucose. This hypoglycemic property supports-its usein folkloric medicine as an antidiabetic agent and thus suggests a place for it in nutritional therapy in the management of diabetes mellitus and thus as an oral hypoglycaemic agent.

Item Type: Article
Subjects: Open Research Librarians > Biological Science
Depositing User: Unnamed user with email support@open.researchlibrarians.com
Date Deposited: 13 Jun 2023 07:43
Last Modified: 29 Jan 2024 06:21
URI: http://stm.e4journal.com/id/eprint/1078

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