Akande, T. and Balogun, S. T. and Abdullahi, H. and Ogundeko, T. O. and Ramyil, M. S. (2015) Glycaemic Evaluation of Murraya koenigii in Alloxan-induced Diabetic Rabbits. International Journal of Biochemistry Research & Review, 7 (4). pp. 175-181. ISSN 2231086X
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Abstract
Background: Study was aimed to evaluate the antidiabetic activity of Murraya koenigii, a traditional medicinal plant (Curry leaf) in normoglycemic and alloxan-induced diabetes rabbits.
Methods: Antidiabetic activity of aqueous extract of M. koenigii in 100, 200 300 mg/k doses was determined by estimating blood glucose before and at 1, 2, 4, 8, 24, and 72 hours post treatment intervals in treated rabbits.
Results: Aqueous extract of Murraya koenigii showed a dose dependent antidiabetic activity with maximum effect established at 300 mg/kg. The extract also exhibited a significant (p<0.05) dose- dependent hypoglycemic effect on normal and alloxan-induced diabetic rabbits.
Conclusion: Murraya koenigii causes a reduction in blood glucose. This hypoglycemic property supports-its usein folkloric medicine as an antidiabetic agent and thus suggests a place for it in nutritional therapy in the management of diabetes mellitus and thus as an oral hypoglycaemic agent.
Item Type: | Article |
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Subjects: | Open Research Librarians > Biological Science |
Depositing User: | Unnamed user with email support@open.researchlibrarians.com |
Date Deposited: | 13 Jun 2023 07:43 |
Last Modified: | 29 Jan 2024 06:21 |
URI: | http://stm.e4journal.com/id/eprint/1078 |