Gallium 68-Fibroblast Activation Protein Inhibitor: PET/CT Improves Diagnosis of Neurocysticercosis

Moradiya, Priyankkumar G. and Mahajan, Rahul S. and Solav, Shrikant V. and Savale, Shailendra V. and Khajindar, Gauri S. and Jagtap, Rajlaxmi R. and Solav, Aman S. and Balani, Suresh L. (2023) Gallium 68-Fibroblast Activation Protein Inhibitor: PET/CT Improves Diagnosis of Neurocysticercosis. Asian Journal of Research in Infectious Diseases, 14 (2). pp. 30-35. ISSN 2582-3221

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Abstract

F18-FDG (Fluorine18- fluoro-deoxyglucose) Positron emission tomography/computerized tomography scan (PET/CT Scan) scan shows intense physiologic uptake in the brain parenchyma. This prevents evaluation of small cerebral lesions. Ga-68-FAPI (Gallium68- Fibroblast activation protein inhibitor) does not localize in normal brain parenchyma. Hence, it can detect cerebral lesions which concentrate the tracer. We report a case of neurocysticercosis in a 32 years old female who presented with headache, nausea and one episode of seizure. MRI brain raised possibility of tuberculoma over neurocysticercosis. There was a hypometabolic area in the right temporal lobe as revealed by F-18-FDG PET/CT, with no FDG avid lesions or lymph nodes identified in the body. Ga68-FAPI PET/CT was performed which showed increased tracer uptake within the right temporal lobe lesion. A focal FAPI uptake was also noted in a tiny hypodense lesion in the left internal oblique muscle of abdomen, which showed signal characteristics of intramuscular cysticercosis on limited MRI study.

Item Type: Article
Subjects: Open Research Librarians > Medical Science
Depositing User: Unnamed user with email support@open.researchlibrarians.com
Date Deposited: 21 Sep 2023 11:12
Last Modified: 21 Sep 2023 11:12
URI: http://stm.e4journal.com/id/eprint/1530

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