D. M., Azizova and R. A., Sabirova (2023) The Effect of Biomays on Lipoprotein Receptors in the Dynamics of Development of Experimental Atherosclerosis. Journal of Advances in Medicine and Medical Research, 35 (20). pp. 265-272. ISSN 2456-8899
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Abstract
In Asia, wheat sprouts (OP) has long been used as a traditional herbal medicine. Polikozanol, vitamins and polyunsaturated fatty acids - have different biological activity: anti-inflammatory, antioxidant, antidiabetic and lipid-lowering.
Aim: Investigate the effect of biomays on lipoprotein receptors in the dynamics of development of experimental atherosclerosis
Materials and Methods of Research: We decided to study the effect of the domestic drug "Biomays" in the treatment of experimental atherosclerosis. The study involved 5 groups of rabbits: 1st - intact (normal), 2nd - rabbits with hypercholesterolemia, 3rd - treatment with ultrax, 4th - treatment with biomice, 5th - received mixed treatment. Investigated the concentration of LOX- 1 and LDLR on the 60th, 70th, 80th and 90th days of hypercholesterolemia.
Results: Thus, the combination of Biomays and Ultrox has the most beneficial effect on LOX- 1 and rLDL parameters than monotherapy. In animals treated with both statins and Biomays, plasma LOX - 1 ligand levels were maintained at lower levels than untreated rabbits.
Conclusion: We have found that the use of a statin in combination with dietary supplements "Biomays" (Maysara) has a synergistic effect improves the expression of r LDL and LDL uptake.
Item Type: | Article |
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Subjects: | Open Research Librarians > Agricultural and Food Science |
Depositing User: | Unnamed user with email support@open.researchlibrarians.com |
Date Deposited: | 07 Oct 2023 07:53 |
Last Modified: | 07 Oct 2023 07:53 |
URI: | http://stm.e4journal.com/id/eprint/1664 |