Mathematical model of skin autofluorescence induced by 450 nm laser

Artemyev, Dmitry (2018) Mathematical model of skin autofluorescence induced by 450 nm laser. Journal of Biomedical Photonics & Engineering, 4 (2). 020303. ISSN 24112844

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Abstract

Optical methods are increasingly being used for the early diagnosis of skin cancer. This approach allows for detecting the component composition changes of tissue in a non-invasive manner. Autofluorescence spectroscopy is a sensitive method for tumor diagnosis and the method availability distinguishes it among other approaches. This work is devoted to fluorescence modeling of skin tissues induced by 450 nm radiation. A multilayer skin model was developed using a set of fluorophores (eumelanin, lipofuscin, riboflavin, beta-carotene, bilirubin) matched with excitation radiation. Model autofluorescence spectra of normal skin tissues of the northern phenotype and pathological changes were obtained. The results were compared with the results of previous experimental studies of ex vivo autofluorescence spectra of the skin and neoplasms.

Item Type: Article
Subjects: Open Research Librarians > Multidisciplinary
Depositing User: Unnamed user with email support@open.researchlibrarians.com
Date Deposited: 20 Feb 2023 10:06
Last Modified: 15 Feb 2024 04:22
URI: http://stm.e4journal.com/id/eprint/187

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