COMPARATIVE STUDY OF DOWNSTA6IN6/PAP SMEAR/COLPOSCOPY/COLPOSCOPIC BIOPSY IN THE DETECTION OF CERVICAL PATHOLOGY

Background: Cancer cervix continues to be the most common genital cancer accounting for 80% of female genital cancer. It is the leading cause for mortality & morbidity among women worldwide.

Materials and Methods: This study was a prospective study conducted in the Department of Obstetrics and Gynecology during the period of July 2010 to Sep 2011 in 250 women who fulfilled the inclusion criteria. 5.5% of the study group belonged to other religions. Cytology, Colposcopy and HPE showed more abnormalities in Hindus. 2

Results: 4.2% of Hindus showed dysplasia on HPE. Among the para 1 to 2, 17.5% had dysplasia on HPE, among the para 3 to 4, 22.2% had dysplasia on HPE and among the para 5 and above, 46.2% had dysplasia· on HPE showing high incidence of dysplasia in the multiparty. The incidence of dysplasia was found to be high among the lower socio-economic groups.(5.9% of class III,25% of class IV and 29.8% of class V had dysplasia on HPE. 33.9% of women who got married at less than 19 years and 10.4% of women married between 20-29 years had dysplasia on HPE showing the high incidence of dysplasia in women with early coitarche. 68.2% of the patients had leucorrhoea as presenting symptoms, of which 22.7% had dysplasia on HPE,1.3% had malignancy on biopsy.2.7% of the patients had postictal bleeding, of which 33.3% had dysplasia on HPE and 33.3% had malignancy on HPE indicating the high incidence of dysplasia in patients with Postictal bleeding and leucorrhoea.

Conclusion: Downsta6in6/Pap Smear is an easy and perspective method and its importance lies in teaching, diagnosis and management of cervical lesions, neoplastic and non- neoplastic.