INFLUENCE OF BIOCHEMICAL CHANGES INDUCED BY DMBA THROUGH THE METHANOLIC MACERATIVES OF PRE-PUPAL STAGES OF BLACK SOLDIER FLY, Hermetia illucens (L.) (MMPPSBSF) IN RATS

The preservative role of the methanolic maceratives of pre-pupal stages of black soldier fly, Hermetia illucens (L.) (MMPPSBSF) was assessed against the 7,12-dimethylbenz[a]anthracene (DMBA)-induced changes in biochemical parameters in blood of rats. Administration of DMBA in the experimental animals (rat, Rattus norwegicus L.) caused decrease in levels of total proteins, albumin and globulin; elevation of urea, uric acid and creatinine levels and elevation of the velocity of biochemical reactions catalysed by the enzyme Asparate-Aminotransferase (AST); enzyme Alanine Aminotransferase (ALT) and enzyme Lactate dehydrogenase (LDH). Treating the experimental animals (rat, Rattus norwegicus L.) with Methanol Extractives of Pre-pupal Stages of Black Soldier Fly (MEPSBSF) in present attempt was found to cause a significant increase in the levels of total proteins, albumin and globulin in the serum. Methanol Extractives of Pre-pupal Stages of Black Soldier Fly (MEPSBSF) thus, providing protection through maintenance of level of the total proteins, albumin and globulin in the serum. Use of Methanol Extractives of Pre-pupal Stages of Black Soldier Fly (MEPSBSF) may open a new avenue to control the damages caused by the carcinogens.