Biological Studies of Newly Synthesized Benzo[d][1,2,3]triazole Derivatives

Bhardwaj, Bharti and Bhagat, Sunita (2019) Biological Studies of Newly Synthesized Benzo[d][1,2,3]triazole Derivatives. In: Theory and Applications of Chemistry Vol. 3. B P International, pp. 81-90. ISBN 978-93-89246-97-1

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Abstract

The study of heterocyclic systems provides most fascinating field for exploration in view of variety of
interesting and intricate reactions, which lead to synthesis of unusual systems having diversities in
their skeletal pattern. In this context, various new heterocycles and derivatives are synthesized with
increased biological activities and less toxicity. Benzo-fused azoles containing three heteroatoms,
specially, benzo[d][1,2,3]triazole, has received great attention, these days, for their chemical and
biological properties and many of them are used as medicines for various diseases. Many researches
have also shown that when heterocyclic and aliphatic secondary amines are introduced in a variety of
heterocyclic compounds, the resulting compounds have been found to possess enhanced biological
activities. Therefore aim of our research was to hook benzotriazole scaffold with these amines with a
help of suitable linker in thirst of obtaining the resulting synthesized molecules possessing high and
varied biological activities which can be useful to mankind in future. We have synthesized Naminoalkylated
derivatives of benzo[d][1,2,3]triazole. All the synthesized compounds were fully
characterized on the basis of their detailed spectral studies and were evaluated for their antimicrobial
activities in vitro.

Item Type: Book Section
Subjects: Open Research Librarians > Chemical Science
Depositing User: Unnamed user with email support@open.researchlibrarians.com
Date Deposited: 06 Dec 2023 04:37
Last Modified: 06 Dec 2023 04:37
URI: http://stm.e4journal.com/id/eprint/2102

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