Al Quntar, Abed Al Aziz and Abasy, Ibrahim and Dweik, Hasan and Maffei, Michel and Dembitsky, Valery M. (2023) Aminated (Cyclopropylmethyl)Phosphonates: Synthesis and Anti-Pancreatic Cancer Activity. International Journal of Organic Chemistry, 13 (04). pp. 129-136. ISSN 2161-4687
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Abstract
Buoyed by the extensive research on the wide-range biological activities of aminophosphonates, a novel class of aminated (cyclopropylmethyl)phosphor-nates compounds was synthesized from diethyl ((1-(3-chloropropyl)cyclopropyl)methyl)phosphonate and various amines in the presence of Hunig’s base. Upon biological activity screening these compounds demonstrated encouraging anti-pancreatic cancer properties at low micromolar concentrations.
Item Type: | Article |
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Subjects: | Open Research Librarians > Chemical Science |
Depositing User: | Unnamed user with email support@open.researchlibrarians.com |
Date Deposited: | 26 Dec 2023 08:05 |
Last Modified: | 26 Dec 2023 08:05 |
URI: | http://stm.e4journal.com/id/eprint/2400 |