Synthesis Spectroscopy and Computational Studies of Manganese (II) Complexes Incorporating (N,O)(O,O`) Ligands and Their Biological Activity

Abokhater, Rania Ahmad and Ashoor, Salem Eltuhami and Gadir, Suad A. (2019) Synthesis Spectroscopy and Computational Studies of Manganese (II) Complexes Incorporating (N,O)(O,O`) Ligands and Their Biological Activity. Asian Journal of Applied Chemistry Research, 3 (3). pp. 1-10. ISSN 2582-0273

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Abstract

Manganese (II) complexes were synthesized via the reaction equimolar quantity of Manganese(II) chloride-hydrate (MnCl2.6H2O) with Chiral saccharides such {(OH)5(CH2)(C5H5)O} or {(OH)6(CH2)(C5H5)O} and (C9H7NO) as secondary ligands [Mn(C9H7NO){(OH)5(CH2)(C5H5)O}]Cl2 (C1), [Mn(QH){(OH)6(CH2)(C5H5)O}]Cl2 (C2), respectively where (C9H7NO) is 8-hydroxyquinoline, {(OH)5(CH2)(C5H5)O} Dextrose (Dex), {(OH)6(CH2)(C5H5)O} fructose (fru). Theses complexes were characterized by UV-vis, IR spectroscopy, tandem mass spectrometry and elemental analysis.

The complexes have been found to have square planer geometry as the optimization method. The molecular geometries obtained from XRD data.

The pre-optimized to standard convergence criteria using the basis Minimize Energy to Minimum.

The isolated compounds were screened for its antibacterial activity against six standard human pathogens (Staphylococcus aureus, Streptococcus spp., Escherichia coli, Klebsiella spp., Psuedomones spp. and Protues spp.) and the results were obtained. About 10 to 70% for complex (C1) and about 10 to 60% for complex (C2) of the activity.

Item Type: Article
Subjects: Open Research Librarians > Chemical Science
Depositing User: Unnamed user with email support@open.researchlibrarians.com
Date Deposited: 12 Apr 2023 05:17
Last Modified: 11 May 2024 08:58
URI: http://stm.e4journal.com/id/eprint/650

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