Role of Exosomes in Brain Diseases

Zhang, Nan and He, Fengling and Li, Ting and Chen, Jinzhi and Jiang, Liping and Ouyang, Xin-Ping and Zuo, Lielian (2021) Role of Exosomes in Brain Diseases. Frontiers in Cellular Neuroscience, 15. ISSN 1662-5102

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Abstract

Exosomes are a subset of extracellular vesicles that act as messengers to facilitate communication between cells. Non-coding RNAs, proteins, lipids, and microRNAs are delivered by the exosomes to target molecules (such as proteins, mRNAs, or DNA) of host cells, thereby playing a key role in the maintenance of normal brain function. However, exosomes are also involved in the occurrence, prognosis, and clinical treatment of brain diseases, such as Alzheimer's disease, Parkinson's disease, stroke, and traumatic brain injury. In this review, we have summarized novel findings that elucidate the role of exosomes in the occurrence, prognosis, and treatment of brain diseases.

Item Type: Article
Subjects: Open Research Librarians > Medical Science
Depositing User: Unnamed user with email support@open.researchlibrarians.com
Date Deposited: 12 Apr 2023 07:42
Last Modified: 26 Feb 2024 04:31
URI: http://stm.e4journal.com/id/eprint/655

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